Adherence to Artemisinin Combination Therapy for the treatment of uncomplicated malaria in the Democratic Republic of the Congo
M. Ruby Siddiqui,Andrew Willis,Karla Bil,Jatinder Singh,Eric Mukomena Sompwe,Cono Ariti
Despite a wealth of natural resources, the Democratic Republic of the Congo (DRC) has one of the lowest per capita incomes in the world. Médecins Sans Frontières-Operational Centre Amsterdam (MSF-OCA) has been working in the provinces of North Kivu and South Kivu since the early 1990s and in Katanga since 2003. MSF-OCA operates....
Stability, orientation and position preference of the stem region (residues 689-703) in Hepatitis C Virus (HCV) envelope glycoprotein E2: a molecular dynamics study
Rahmad Akbar,Siti Azma Jusoh
Envelope glycoproteins E1 and E2 are essential for the initial binding and internalization of Hepatitis C Virus (HCV) into host cells. Both glycoproteins have been shown to interact as a non-covalent heterodimer during biosynthesis. In our previous studies, we demonstrated that the unfolding behavior of the E2 TM helix monomer w....
The effect of morning versus evening administration of empagliflozin on its pharmacokinetics and pharmacodynamics characteristics in healthy adults: a two-way crossover, non-randomised trial
Rana M. ElDash,Mohamed A. Raslan,Sara M. Shaheen,Nagwa Ali Sabri
Diabetes mellitus (DM) is one of the leading causes of death in the world. It has become one of the most critically medical and socially impacted diseases of the 21. Chronopharmacology is the field of study concerned with the circadian rhythm of drugs regarding its pharmacokinetics/pharmacodynamics and pharmacological action; it....
Molecular docking analysis of selected phytochemicals on two SARS-CoV-2 targets
Amaka Ubani,Francis Agwom,Oluwatoyin Ruth Morenikeji,Nathan Yakubu Shehu,Emmanuel Arinze Umera,Uzal Umar,Simeon Omale,John Chinyere Aguiyi,Nnaemeka Emmanuel Nnadi,Pam Dachung Luka
Since 2003, three coronaviruses have been associated with pneumonia, the first was severe acute respiratory syndrome coronavirus (SARS-CoV-1). The entry into the host cell by the coronaviruses is usually mediated by the spike (S) glycoprotein. Possibly, potent inhibitors of these two targets will be able to interfere with the S....
Analysis of the health product pipeline for poverty-related and neglected diseases using the Portfolio-to-Impact (P2I) modeling tool
Shashika Bandara,Nick Chapman,Vipul Chowdhary,Anna Doubell,Amelia Hynen,George Rugarabamu,Alexander Gunn,Gavin Yamey
A growing body of evidence has shown that the ambitious global health goals established by the international health community, including the health-related Sustainable Development Goals (SDGs), are unlikely to be achieved with today’s health technologies alone. For example, the 2013 report of the. There are several signs suggest....
Apoptosis induction on human breast cancer T47D cell line by extracts of Ancorina sp.
Woro Anindito Sri Tunjung,Puspa Restu Sayekti
Breast cancer is the second leading cause of death in women after cervical cancer. In 2016 breast cancer cases have occurred in 40 per 100,000 women in Indonesia. There are many cancer treatment methods such as anti-angiogenesis therapy. Previous studies found many natural apoptosis-inducing compounds isolated from marine sponge....
Shared Decision Making
Dr Leanne Brown, Nurse Practitoner
This presentation will provide an overview regarding the role shared decision making can have within assisting patient with advanced kidney disease make treatment choices. It will also cover current shared decision making models and barriers and facilitators in implementing shared decision making into routine clinical care.
Procédures de nettoyage du matériel de réanimation
GHM
Cleaning Resuscitation Equipment - Procédures de nettoyage du matériel de réanimation
Neonatal Jaundice, Kenya & Tanzania
Dr Syed Furrukh Jamil ,MRCPCH, FRCPCH,FHEA
The American Academy of Pediatrics This presentation is a project funded by UNICEF to the American Academy of Pediatrics to provide techincal expertise in the form of newborn care telementoring.
Neonatal Jaundice, Pakistan
Yvonne Vaucher, M.D.,M.P.H,FAAP
The American Academy of Pediatrics This presentation is a project funded by UNICEF to the American Academy of Pediatrics to provide techincal expertise in the form of newborn care telementoring.
Respiratory Infection
Francine Uzamuhoza, RN and Priscille Musabirema, RME
Rwanda Nurses and Midwives Union Definition of respiratory infection Causes of respiratory infection Transmission ways of respiratory infection Signs and symptoms of upper and lower respiratory infection Diagnostic test used to confirm respiratory infection Management of respiratory infections Preventions methods and t....
Newborn Examination
Mr. Ntirenganya, Sylvestre, RN, BScN, PGCTLHE, MScN and Dr. Madeleine, Mukeshimana, RMHN, MScN, PhD
This course is made of: Principles of newborn examination Newborn admission care Examination of the newborn at birth Types and stages of newborn assessment Examination of the newborn within 24 hours Examination of the newborn at discharge Examination on follow-up System by system examination
Identifying the spatial patterning characteristics of HIV positive clients not linked to care using a geographic information system
Kevin Rombosia,Nelly Rangara,Elizabeth Oele,Nancy Kirui,Douglas Olaka,Evans Ondura,Bernard Mitto
For many years, the analysis and use of spatial data has guided public health efforts, and Dr. John Snow, who is often credited as the founder of epidemiology, is a classic example of using this type of data. UNAIDS. Investigating the spatial patterning of diseases is an epidemiology tool that provides greater understanding of t....
Africa’s response to the COVID-19 pandemic: A review of the nature of the virus, impacts and implications for preparedness
Kingsley Badu,Jessica P.R. Thorn,Nowsheen Goonoo,Natisha Dukhi,Adeniyi Francis Fagbamigbe,Benard W. Kulohoma,Kolapo Oyebola,Sara I. Abdelsalam,Wesley Doorsamy,Olawale Awe,Augustina Angelina Sylverken,Anthony Egeru,Jesse Gitaka
As the world continues to experience climatic and ecosystem changes and increased human migration, there has been a surge of novel and re-emerging pathogens. Over the past three decades, up to 30 new human pathogens have been detected, 75% of which have animal origin (. COVID-19 triggers respiratory difficulties for which the SA....
Autism seminary for public engagement: evaluation of knowledge and attitudes of traditional medical practitioners in Mali
Modibo Sangare,Bakary Dembele,Amadou Toure,Seidina Diakite,Gordon Awandare,Modibo Kouyate,Seydou Doumbia,Mahamadou Diakite,Arouna Togora,Souleymane Coulibaly,Housseini Dolo
Despite autism spectrum disorders (ASD) being ubiquitous in Africa (. Combining herbal medicines with conventional treatment seem to have a positive effect on the treatment of ASD in children (n
Cancer in Kenya: types and infection-attributable. Data from the adult population of two National referral hospitals (2008-2012)
Lucy Wanjiku Macharia,Marianne Wanjiru Mureithi,Omu Anzala
Cancer in Africa is an emerging health problem where about 847,000 new cancer cases and 591,000 deaths occurred in 2012, with about three quarters of these occurring in the sub-Saharan region. Nearly 31% of the total cancer burden in sub-Saharan Africa is attributable to infections. Information on the burden of cancer and especi....
Kenya’s response to the COVID-19 pandemic: a balance between minimising morbidity and adverse economic impact
Edwin N. Wangari,Peter Gichuki,Angelyne A. Abuor,Jacqueline Wambui,Stephen O. Okeyo,Henry T.N. Oyatsi,Shadrack Odikara,Benard W. Kulohoma
The views expressed in this article are those of the authors. Publication in AAS Open Research does not imply endorsement by the AAS.. The world is experiencing a significant public health threat due to the global coronavirus disease 2019 (COVID-19) pandemic. The COVID-19 pandemic overshadows recent outbreaks of severe acute res....
The nexus between improved water supply and water-borne diseases in urban areas in Africa: a scoping review
Nyamai Mutono,Jim A Wright,Henry Mutembei,Josphat Muema,Mair L.H Thomas,Mumbua Mutunga,Samuel Mwangi Thumbi
The sub-Saharan Africa (SSA) has experienced the highest annual urban population growth rate (more than 3.5%) in the world. Globally, it is estimated that one in every two people will be living in water stressed areas by 2025 increasing the challenge of water supply. More than half a million deaths in SSA have been attributed to....
Study design
Dr Nopakoon Nantsupawat
Outlines - How to select a study design - Common types of study designs - Major functional features of each study designs
Vaccination
Jhpiego
Principles of Disease Management and Control III (Community Health Nursing Programme) - Immunity and Diseases - Vaccines - Expanded Programme of Immunization Principles of Disease Management and Control III (Community Health Nursing Programme) -Immunization Systems and Operations Public Health Nursing (Midwifery Progr....
Infection Prevention & Control in Healthcare Settings
Jhpiego
MIP 111 Microbiology and Infection Prevention and Control (RM Programme) NAP 034 Principles of Disease MMIP 111 Microbiology and Infection Prevention and Control (RGN Programme)anagement and Control I (RNAP)
Effects of Emergencies on Health and Nutrition - An Advanced Guide
Humanitarian Leadership Academy, Save the Children
Kaya This e-learning course explores the effects of emergencies on health and nutrition. This is the advanced course and builds on what you learned in the introductory course. This course consists of a causal analysis of 10 main risk factors to health and nutrition, in relation to preventable causes of excess death in emerge....
Evidence-based Malaria SBCC 2: Formative Research for SBCC: Do You Know Your Audience?
Michelle R. Kaufman, PhD
John Hopkins University This eLearning series consists of 5 modules. This is module 2, entitled 'Formative Research for SBCC: Do You Know Your Audience?'. The module is presented by Dr. Michelle R. Kaufman and will introduce participants to the basics of formative research for informing SBCC programs, using examples specific t....