Coronavirus disease 2019 drug discovery through molecular docking
Sweta Singh,Hector Florez
Coronavirus Disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), that is responsible for respiratory illness and probably many more is yet to be discovered. This novel virus was first identified on 30. Then, it is necessary for the rapid development and approval of a vaccine, whi....
Hub genes in a pan-cancer co-expression network show potential for predicting drug responses
Francisco Azuaje,Tony Kaoma,Céline Jeanty,Petr V. Nazarov,Arnaud Muller,Sang-Yoon Kim,Gunnar Dittmar,Anna Golebiewska,Simone P. Niclou
The analysis of networks extracted from different types of “omics” data is a useful strategy to enable the characterization and prediction of meaningful properties of the underlying complex biological systems. Addressing the above-mentioned challenge is now possible thanks to the availability of large collections of data origina....
The effect of silver nanoparticles incorporation in the self-etch adhesive system on its antibacterial activity and degree of conversion: an in-vitro study
Heba F. Mohammed,Mona I. Riad
Dental resin composite is a widely used restorative material that has superior aesthetic properties and strong bonding ability to the tooth structure in comparison to other restorative materials like amalgam. Silver is an antimicrobial agent that has broad spectrum activity against gram positive and gram negative bacterian....
Early assessment of antiretroviral efficacy is critical to prevent the emergence of resistance mutations in HIV-tuberculosis coinfected patients: a substudy of the CARINEMO-ANRS12146 trial
Elisabeth Baudin,Nilesh Bhatt,Christine Rouzioux,Micaela Serafini,Lucas Molfino,Ilesh Jani,Anne-Marie Taburet,Maryline Bonnet,Alexandra Calmy
Antiretroviral therapy (ART) aims to sustain virological suppression, which is associated with a clinical benefit and immune recovery. It also prevents HIV transmission and limits the emergence of antiretroviral (ARV) drug resistance. In a recent meta-analysis, Gupta. In 2016, 80% of the worldwide prescription of ART-included ef....
Post-Ebola Community Health Worker programme performance in Kenema District, Sierra Leone: A long way to go!
Harold Thomas,Katrina Hann,Mohamed Vandi,Joseph Bengalie Sesay,Koi Sylvester Alpha,Robinah Najjemba
The effect of the 2014–2015 West African Ebola outbreak on Community Health Worker (CHW) services in Kenema district, Sierra Leone, was assessed through a retrospective cross-sectional study comparing CHW reporting and services before (June 2013-April 2014), during (June 2014-April 2015) and post-outbreak (November 2015-April 20....
Knowledge of pastoralists on livestock diseases and exposure assessment to brucellosis within rural and peri-urban areas in Kajiado, Kenya
Joshua Onono,Penina Mutua,Philip Kitala,Peter Gathura
Brucellosis is a neglected bacterial zoonosis with global distribution, and it has been reported in 56 countries with more than 500,000 new human cases reported annually (. In Kenya, brucellosis was first reported in 1916 with the first case confirmed in a laboratory in 1931 (. The pastoralist communities are highly dependent on....
Could night-guards be used as a simple method to detect leached-elements from dental restorations intra-orally? A study on amalgam restorations
Rasha Mohamed Abdelraouf
Determination of leached-elements from dental restorations has been investigated as a result of exposure to oral conditions. On the other hand,. Yet, measuring the released elements in humans may be best. Several studies quantified the excretion of mercury in urine, hair and nails of patients with dental amalgam-restorations and....
In vitro regulation of reactive oxygen species formation in red blood cells of homozygous sickle cell patients using Vitamin C
Ogechukwu Egini,Edouard Guillaume,Titilope Adeyemo,Chiemeziem Nwanyanwu,Fnu Shweta,Eric Jaffe
Sickle cell anemia is a single-nucleotide polymorphism due to substitution of glutamic acid by valine at position 6 of the B-globin chain. ROS formation is maximal during the reperfusion state when there is increased formation of methemoglobin and superoxide ion due to electron transfers that occur between the heme iron and oxyg....
Continuous and intermittent exposure of neonatal rat calvarial cells to PTHrP (1-36) inhibits bone nodule mineralization in vitro by downregulating bone sialoprotein expression via the cAMP signaling pathway
Suzan A Kamel,John A Yee
Parathyroid-hormone-related protein (PTHrP) is the causative factor of humoral hypercalcemia of malignancy. The amino terminus of PTHrP has strong homology with the comparable region of parathyroid hormone (PTH). In several tissues, including bone, it has been reported that PTHrP and PTH1R mRNAs and/or proteins are expressed by....
Leading a Healthy Workplace Environment
Keith Carlson, BSN, RN, NC-BC
In the 21st century healthcare and nursing ecosystem, increased attention is being paid to the creation of healthy work environments and positive workplace culture. Nurses need to feel valued, supported, and engaged. So how can nurse leaders bring these initiatives to life and help to improve nurse retention and employee engagem....
Making Data Work for Nursing Using Nursing Research and Evidence-based Practice to Affect Nursing
Terri Gaffney, PhD, MPA, RN, Mary Del Guidice, MSN, BS, RN, CENP and Kathryn Farrell, MSN, RN
This course brings you research and best practices about recovering medication errors thereby enhancing patient safety, a research mentorship program, and fiscal stewardship to improve nurse staffing.
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PRIMARY COURSE
Mr Samuel L Jackson
Faculty of Orthopaedic Academy Dr.Firas Arnaout MD MSc FRCS – Consultant Orthopaedic Surgeon – Director of Education
Topical anaesthetics
Zoe Greenwood
This session looks at which topical anaesthetics are available, including techniques for their application, uses, disadvantages and alternatives.
Inhalation Sedation Equipment
Kathy Wilson
This session describes the equipment required for the administration of inhalation sedation. Details of the safety features and equipment checks are also covered.
Respiratory physiology relevant to conscious sedation
John Lyne
This session will cover the basic mechanism of gas exchange. The importance of the oxygen dissociation curve in sedation practice will also be discussed.
Suicide and Substance Use
Gloria J. Baciewic and Timothy J. Wiegand
1.25 Hours
A Deep Dive into Complex Addiction Cases with Leading Experts! The ACMT Addiction Toxicology Case Conference webinar series discusses Addiction/Toxicology cases in an interactive fashion featuring experts from Addiction Medicine, Addiction Psychiatry, and Medical Toxicology. Case 1: "I Don't Care if I Don't Wake Up" - Suic....
Patient-centred Information Gathering
Grant Simic, BMedSci
1.00 Hours
Uncover deep insights about the nature of patient symptoms, achieve earlier and more accurate diagnoses, and improve patient experience. This interactive online course shows how to facilitate patient-centered encounters, gather critical information, increase patient understanding, and attain greater medication adherence.
General Principles of Orthopaedic Practice
David Hughes
0.75 Hours
Explore core concepts in orthopaedic surgery, diagnosis, and treatment. Develop a strong foundation for further study and clinical practice.
Orthopaedic Implants & Appliances
Mr Mohammed As-Sultany and Rajesh Bahadur Lakhey
1.50 Hours
Explore the world of orthopaedic implants & appliances. Gain knowledge for selecting & using them effectively in patient care.
Practical & Surgical Orthopaedic Skills
S. Kamat, Mr Diab, Mr. Mahmoud Rahuna, Rajesh Bahadur Lakhey
2.25 Hours
Develop your surgical skillset with expert instruction and hands-on practice in a simulated environment. Ideal for orthopaedic residents and surgeons seeking to refine their surgical technique.
Chemsex
Gloria J. Baciewic and Timothy J. Wiegand
1.25 Hours
A Deep Dive into Complex Addiction Cases with Leading Experts! The ACMT Addiction Toxicology Case Conference webinar series discusses Addiction/Toxicology cases in an interactive fashion featuring experts from Addiction Medicine, Addiction Psychiatry, and Medical Toxicology. Case 1: Getting "handsy" at the Gas Station Cas....
Introduction to Asthma in General Practice eLearning
Jeshni Amblum-Almer and Ameet Gordhan
6.00 Hours
This course is designed to enhance the knowledge and skills of healthcareprofessionals working in general practice in the UK. It aims to provide a comprehensiveunderstanding of asthma management based on the latest recommendations andguidelines, with a specific focus on primary care. Participants will gain the necessaryexpertise....
Introducing the Tuberculosis Diagnostic Network Assessment (TB-DNA) Tool
Dr Alex Durena, Dr Anteneh Kassa Mekonnen and Prof Moses Joloba
The May 2023 LabCoP ECHO session jointly organised by the African Society for Laboratory Medicine and the Global Laboratory Initiative (GLI) featured the Tuberculosis Diagnostic Network Assessment (TB-DNA) tool. TB-DNA is a country-driven process that assesses the functionality of the national tuberculosis (TB) diagnostic netwo....
Strengthening COVID-19 Diagnostic and Laboratory Systems Investments in Africa through Partnerships
The African Society for Laboratory Medicine (ASLM)
On 31 March 2022, ASLM’s LabCoP convened an ECHO session on supporting the implementation of diagnostics and laboratory systems investments for COVID-19 in the African region. With funding from The Global Fund and through their Stellar Project, and in collaboration with Africa CDC, ASLM, Association of Public Health Laboratories....