Sickle Cell Disease: Pathophysiology and Clinical Manifestations in Children and Adolescents
By The Hospital for Sick Children (SickKids) and Ghana College of Nurses and Midwives
In this course, Sickle Cell Disease: Pathophysiology and Clinical Manifestations in Children and Adolescents, you will learn about what is happening at the microscopic level in Sickle Cell Disease (SCD). Through interactive activities, you will learn about how SCD causes problems in the body, and how these might present. It is....
Renal Cell Cancer 2
Peter Guest
0.75 Hours
The first part of this session continues on the topic of renal cell cancer or carcinoma (RCC) which was introduced in the session Renal Cell Cancer 1, by looking at inherited disorders and the incidence of RCC in inherited disorders and in end-stage renal failure (ESRF). The second half goes on to look at other tumours affecting....
Breast Disease: Breast Pain
Dan Cocker
0.25 Hours
This session is designed to introduce the user to the common causes of breast pain.
Primary Adrenal Insufficiency
Matthew Carter
0.5 Hours
This session aims provide a greater awareness of adrenal insufficiency in paramedic practice.
Peripheral Vascular Disease Chronic Limb Ischaemia
Devender Mittapalli
0.75 Hours
This session covers essential information on chronic limb ischaemia required to pass the MRCS examination. It also provides the essential knowledge and skills required for Foundation and Core surgical trainees in their day-to-day practice.
AKI - Differential Diagnosis
John Firth
0.5 Hours
This session will explain how to make the diagnosis of acute kidney injury, and how to determine whether it is caused by pre-renal failure/acute tubular necrosis, a renal inflammatory condition, or urinary obstruction.
Adrenal Masses
Sheila Rankin and Rodney Reznek
0.5 Hours
Masses of the adrenal gland can be benign or malignant, unilateral or bilateral. This session describes the imaging techniques and features that will help to classify an adrenal mass.
AKI - Life-threatening Complications
Sanjay Ojha
0.5 Hours
This session will explain how to recognise and manage the life-threatening complications of acute kidney injury, and how to explain the process of emergency dialysis to a patient with acute kidney injury.
Sickle Cell Disease: Acute Management in Children and Adolescents
By The Hospital for Sick Children (SickKids) and Ghana College of Nurses and Midwives
This course is part of a series on Sickle Cell Diseases by the SickKids-Ghana Paediatric Nursing Education Partnership. The series was developed for healthcare workers (nurses, community health nurses, midwives, and physicians) in Ghana, but has broad relevance for healthcare workers in the region and globally. It is recommend....
Influence of different types of whitening tooth pastes on the tooth color, enamel surface roughness and enamel morphology of human teeth
Mohamed Shamel,Mahmoud M. Al-Ankily,Mahmoud M. Bakr
Patients are generally dissatisfied with their present teeth color, as demonstrated by many studies in different regions of the world. Attempts to improve the shade of teeth is presently possible using multiple methods, including professional scaling and prophylaxis performed in the dental clinic, fabrication of tooth crowns and....
Accuracy of linear measurements using low dose cone beam computed tomography protocol versus direct skull linear measurements: An in vitro study
Nora Aly Al Abbady,Reham Mohamed Hamdy,Sahar Hosny El Dessouky
Two-dimensional (2D) imaging techniques have been used in dentistry since 1896. Despite its long clinical success, 2D imaging possesses a number of problems, including superimposition and magnification, which may result in interpretation problems of the images, whether it actually represents the anatomical structures and/or path....
Association between umbilical cord hygiene and neonatal sepsis among neonates presenting to a primary care facility in Nairobi County, Kenya: a case-control study
Phoebe K. Moraa,Marshal M. Mweu,Peter K. Njoroge
Worldwide, neonatal mortality (death occurring within the first 28 days of life) accounted for 45.1% of all child deaths in 2015, representing a 15% increase over a span of 15 years. Owing to the non-specificity of neonatal sepsis’ presentation in neonates, there has been a general lack of consensus on the definition of neonatal....
Fibroblast growth factor-6 enhances CDK2 and MATK expression in microvesicles derived from human stem cells extracted from exfoliated deciduous teeth
Ahmed Othman,Rabab Mubarak,Dina Sabry
Stem cells from human exfoliated deciduous teeth (SHEDs) are a type of adult stem cell acquired from the dental pulp of human exfoliated deciduous teeth. SHEDs stand out from other types of adult stem cells since they possess a remarkable growth and proliferation rate, providing an adequate stem cell source for any prospective c....
Clinical outcomes of zirconia-reinforced lithium silicate partial coverage crowns compared to lithium disilicate partial coverage crowns. A randomized controlled split-mouth clinical study
Hanaa Nassar,Carl H Halim,Hesham A Katamish
High survival rates, fracture resistance and proper marginal integrity of CAD/CAM partial coverage restorations (PCRs) were reported in studies simulating 5-year clinical service. However, clinical behavior of PCRs utilizing morphology driven preparation design was never assessed in randomized clinical trials. Furthermore, long-....
Age, neutrophil lymphocyte ratio, and radiographic assessment of the quantity of lung edema (RALE) score to predict in-hospital mortality in COVID-19 patients: a retrospective study
Anggraini Dwi Sensusiati,Muhammad Amin,Nasronudin Nasronudin,Alfian Nur Rosyid,Nanda Aulya Ramadhan,Rofida Lathifah,Eva Puspitasari,Ria Indah Wahyuningtyas,Erika Soebakti
Cases of pneumonia of unknown etiology were first reported in the city of Wuhan, China, at the end of December 2019. After identification, the etiology of these cases was a new type of coronavirus (. Since December 2019, more than 20 million people have been diagnosed with COVID-19, and more than 700,000 have died (. Several stu....
Seroprevalence and characterisation of herpes simplex virus from human immunodeficiency virus in samples collected from two provinces in South Africa: a retrospective study
Oluwafemi Samuel Obisesan,Nomathamsanqa Patricia Sithebe,Hazel Tumelo Mufhandu
Herpes simplex virus (HSV) is a prevalent organism that belongs to the sub-family of alpha Herpesviridae (. It is important to determine the epidemiology of HSV-1 and HSV-2 because of the disease burden associated with their infection (. The high prevalence of human immunodeficiency virus type 1 (HIV-1) in South Africa (about 7.....
Case Report: Management of idiopathic chylothorax
Maher Abouda,Yangui Ferdaous,Miriam Triki,Mehdi Charfi,Mohamed Ridha Charfi
Chylothorax is characterized by the presence of chyle, which is rich in triglycerides and chylomicrons in the pleural space resulting from damage of the thoracic ductn
Review of the nutritional composition, medicinal, phytochemical and pharmacological properties of Citrus reticulata Blanco (Rutaceae)
Collen Musara,Elizabeth Bosede Aladejana,Silas Mufambi Mudyiwa
Blanco is a large species belonging to the family Rutaceae, with various varieties and hybrids. Mandarins, like other citrus species, are indigenous to the subtropical and tropical zones of Asia, particularly China and Cochin-China. Mandarins, including both monoembryonic and polyembryonic cultivars and many interspecific hybrid....
Maternal and newborn seroprevalence of Hepatitis E virus at Medani Hospital, Sudan
Reem Eltayeb,Gasim I. Gasim,Elhassan M. Elhassan,Halla Abdullahi,Duria A. Rayis,Ishag Adam
Hepatitis E virus (HEV) is a single-stranded RNA virus and an emerging infectious agent where it can cause acute viral hepatitis worldwide with estimated 20 million cases of HEV infection occur globally and 70 000 deaths (. In Sudan, a high mortality rate was reported among pregnant women in an outbreak of HEV in Darfur and in e....
The effect of morning versus evening administration of empagliflozin on its pharmacokinetics and pharmacodynamics characteristics in healthy adults: a two-way crossover, non-randomised trial
Rana M. ElDash,Mohamed A. Raslan,Sara M. Shaheen,Nagwa Ali Sabri
Diabetes mellitus (DM) is one of the leading causes of death in the world. It has become one of the most critically medical and socially impacted diseases of the 21. Chronopharmacology is the field of study concerned with the circadian rhythm of drugs regarding its pharmacokinetics/pharmacodynamics and pharmacological action; it....
Analysis of the health product pipeline for poverty-related and neglected diseases using the Portfolio-to-Impact (P2I) modeling tool
Shashika Bandara,Nick Chapman,Vipul Chowdhary,Anna Doubell,Amelia Hynen,George Rugarabamu,Alexander Gunn,Gavin Yamey
A growing body of evidence has shown that the ambitious global health goals established by the international health community, including the health-related Sustainable Development Goals (SDGs), are unlikely to be achieved with today’s health technologies alone. For example, the 2013 report of the. There are several signs suggest....
Adherence to Artemisinin Combination Therapy for the treatment of uncomplicated malaria in the Democratic Republic of the Congo
M. Ruby Siddiqui,Andrew Willis,Karla Bil,Jatinder Singh,Eric Mukomena Sompwe,Cono Ariti
Despite a wealth of natural resources, the Democratic Republic of the Congo (DRC) has one of the lowest per capita incomes in the world. Médecins Sans Frontières-Operational Centre Amsterdam (MSF-OCA) has been working in the provinces of North Kivu and South Kivu since the early 1990s and in Katanga since 2003. MSF-OCA operates....
Molecular docking analysis of selected phytochemicals on two SARS-CoV-2 targets
Amaka Ubani,Francis Agwom,Oluwatoyin Ruth Morenikeji,Nathan Yakubu Shehu,Emmanuel Arinze Umera,Uzal Umar,Simeon Omale,John Chinyere Aguiyi,Nnaemeka Emmanuel Nnadi,Pam Dachung Luka
Since 2003, three coronaviruses have been associated with pneumonia, the first was severe acute respiratory syndrome coronavirus (SARS-CoV-1). The entry into the host cell by the coronaviruses is usually mediated by the spike (S) glycoprotein. Possibly, potent inhibitors of these two targets will be able to interfere with the S....
Stability, orientation and position preference of the stem region (residues 689-703) in Hepatitis C Virus (HCV) envelope glycoprotein E2: a molecular dynamics study
Rahmad Akbar,Siti Azma Jusoh
Envelope glycoproteins E1 and E2 are essential for the initial binding and internalization of Hepatitis C Virus (HCV) into host cells. Both glycoproteins have been shown to interact as a non-covalent heterodimer during biosynthesis. In our previous studies, we demonstrated that the unfolding behavior of the E2 TM helix monomer w....
Apoptosis induction on human breast cancer T47D cell line by extracts of Ancorina sp.
Woro Anindito Sri Tunjung,Puspa Restu Sayekti
Breast cancer is the second leading cause of death in women after cervical cancer. In 2016 breast cancer cases have occurred in 40 per 100,000 women in Indonesia. There are many cancer treatment methods such as anti-angiogenesis therapy. Previous studies found many natural apoptosis-inducing compounds isolated from marine sponge....