Cell growth inhibition and apoptotic effects of a specific anti-RTFscFv antibody on prostate cancer, but not glioblastoma, cells
Foroogh Nejatollahi,Payam Bayat,Bahareh Moazen
Prostate cancer is the most prevalent malignancy and the second leading cause of cancer-related death among men in the USA and developing countries. Recombinant DNA technology paved the way for the production of recombinant antibody (rAb) fragments, such as single-chain variable fragment (scFv) antibodies, which are composed of....
The prevalence of dental caries among Egyptian children and adolescences and its association with age, socioeconomic status, dietary habits and other risk factors. A cross-sectional study
Marwa M.S. Abbass,Sara Ahmed Mahmoud,Sara El Moshy,Dina Rady,Nermeen AbuBakr,Israa Ahmed Radwan,Attera Ahmed,Ahmed Abdou,Ayoub Al-Jawaldeh
Dental caries is a major public health issue and it is the most widespread chronic disease. In children, dental caries pattern depends on the timing of tooth eruption as well as harmful dietary habit. Therefore, age is considered as an important factor that affects dental caries prevalence in children. It has been estimated that....
Evaluation of retention of knowledge, skill and competency of health workers one year after completion of the Helping Babies Breathe training program in South Sudan
Christopher Vunni Draiko,Khemika Yamarat,Alessio Panza,Judith Draleru
Of the 200,000 children born annually in South Sudan, an estimated 40% die in the first month of life. The transition from intrauterine to extra uterine life requires initiation of breathing which is critical physiological changes required for newborn survival. Research indicates that the majority of newborns initiate breathing....
Fracture resistance and 3D finite element analysis of machined ceramic crowns bonded to endodontically treated molars with two planes versus flat occlusal preparation designs: an in vitro study
Omnia Nabil,Carl Hany Halim,Ashraf Hassan Mokhtar
The best line of treatment to restore root canal treated teeth is one of the highly considered and debatable subjects. The breakthrough of adhesion in dentistry has enhanced the techniques of restoration of endodontically treated teeth. Adhesive composite resin and glass fiber posts have superseded the previously used non-bonded....
Evaluation of postoperative pain in infected root canals after using double antibiotic paste versus calcium hydroxide as intra-canal medication: A randomized controlled trial
Sarah Samir Abouelenien,Salsaby Mohamed Ibrahim,Olfat Gamil Shaker,Geraldine Mohamed Ahmed
Pain is the main symptom in many medical and dental conditions that can significantly alter the person’s general functioning. Several intra-canal medications have been used, including calcium hydroxide which is the most widely used intra-canal medication. It is characterized by its initial bactericidal, bacteriostatic effect and....
Antimicrobial resistance surveillance among gram-negative bacterial isolates from patients in hospitals in Khartoum State, Sudan
Hana Salaheldin Elbadawi,Kamal Mustafa Elhag,Elsheikh Mahgoub,Hisham N. Altayb,Muzamil Mahdi Abdel Hamid
Antimicrobial resistance (AMR) constitutes a continuously growing threat to the effective treatment of microbial infections. AMR surveillance is key for determining the prevalence patterns of AMR, which is fundamental for the development of national and international treatment strategies. Most of the available surveillance data....
Study of Antibodies to Cytolethal Distending Toxin B (CdtB) and Antibodies to Vinculin in Patients with Irritable Bowel Syndrome
Maysaa El Sayed Zaki,Dina Elhammady,Mona Foda Salama,Mostafa Abdelsalam,Asmaa Osama Bakr Osman
Irritable bowel syndrome (IBS) is a common gut disorder that affects approximately 11% of the global population.. The Rome working team recommended classifying subjects with IBS into different sub-groups depending on their bowel habits changes predominance. The IBS sub-groups included IBS with constipation (IBS-C), IBS with diar....
Postoperative pain and antibacterial effect of 980 nm diode laser versus conventional endodontic treatment in necrotic teeth with chronic periapical lesions: A randomized control trial
Dina A. Morsy,Maged Negm,Alaa Diab,Geraldine Ahmed
The therapeutic goal of endodontic treatment in cases of necrotic teeth with chronic periapical lesions is the creation of a sterile, bacteria-free environment in the tooth and at the apex, including the periodontal tissue and the surrounding apical bonen
Invariant death
Steven A. Frank
The coil of a snail’s shell expresses the duality of constraint and process. The logarithmic spiral of growth constrains overall form. Particular snails modulate the process of shell deposition, varying the parameters of the logarithmic spiral. To interpret the variety of snail shells, one must recognize the interplay between br....
The relationships between pancreatic T2* values and pancreatic iron loading with cardiac dysfunctions, hepatic and cardiac iron siderosis among Egyptian children and young adults with β-thalassaemia major and sickle cell disease: a cross-sectional study
Khaled Salama,Amina Abdelsalam,Hadeel Seif Eldin,Eman Youness,Yasmeen Selim,Christine Salama,Gehad Hassanein,Mohamed Samir,Hanan Zekri
The hallmark of chronic hemolytic anemias (CHAs) is premature destruction of erythrocytes. Consequently, it is important to detect silent cardiac dysfunction early before the development of symptomatic heart diseasen
Evaluation of controlled type II diabetics ascending and descending a ramp surface at an imposed speed: A case-control study
Martin G. Rosario,Elizabeth Orozco,Nairoby Babilonia,Greisy Tellez,Francheska Mojica,Maryvi Gonzalez-Sola,Flavia Bayron
Significant gait and balance deficits have been found in persons with type two diabetes mellitus (DMII) compared to individuals without DMII (. As a result of having gait and balance deficits, Dingwell. However, recent evidence suggests that similar gait and balance deficits can be found in individuals with DMII without PN (. In....
Measuring the effectiveness of maternal delivery services: A cross-sectional and qualitative study of perinatal mortality in six primary referral hospitals, Kenya
Richard Ayah,Dismas Ongore,Alfred T.O. Agwanda
The hospital sector represents approximately 45–69% of government health expenditure in sub-Saharan Africa and the effective performance of the sub-sector is therefore critical to overall health system goal achievement. In Kenya, overall health status is measured by indicators including life expectancy, and under-five and matern....
Case Report: Coronary artery stent infection with mycotic aneurysm secondary to tricuspid valve infective endocarditis
Mejdi Ben Messaoud,Nidhal Bouchahda,Marouane Mahjoub,Badii Hmida,Zohra Dridi,Habib Gamra
Infectious complications following percutaneous cardiac interventions are known but not very common. Coronary stent implantation is associated with complications, though rare, such as stent infection or coronary aneurysms resulting from several mechanisms, and needing special investigations for their diagnosis and management. We....
Overuse of prophylactic antibiotics for elective caesarean delivery in Medani Hospital, Sudan
Tahani E. Abbas,Ishag Adam,Elhassan M. Elhassan,Imad Eldin M. Tag Eldin,Mirgani Abdel Rahman
Cesarean delivery (CD) is a procedure mainly performed to save the lives of mother and child to ensure a healthy outcome when normal vaginal delivery is not possible. It is the most common major surgical procedure performed worldwide (. The Cochrane Database of Systematic Reviews has reported that antibiotic prophylaxis has redu....
Maternal age and intracytoplasmic sperm injection outcome in infertile couples at Khartoum, Sudan
Mohamed Ahmed,Osama Shareef,Ishag Adam,Duria Rayis
fertilization (IVF) is recognized as the last treatment option for infertile couples who want biological children, and has been widely accepted as the most important and efficient treatment for infertility (n
The relationship between Helicobacter pylori infection and intestinal parasites in individuals from Khartoum state, Sudan: a case-control study
Yasir Yousif Abd Elbagi,Ahmed Bakheet Abd Alla,Mohammed Baha Eldin Saad
Among the most common diseases in the world are intestinal parasite infections; an estimated 3.5 billion people are affected, and 450 million people are infected (. Health impacts differ with age: the small intestinal protozoa. can be easily identified in all microbiology laboratories using simple techniques (n
Case Report: Root resorption caused after pulp death of adjacent primary molar
Maha M. Azab,Dalia M. Moheb,Osama I. El Shahawy
Root resorption is the physiologic or pathologic loss of dentin and/or cementum and/or bone. Primary teeth can go through either type, but other than resorption during the shedding process resorption is considered pathologic. Inflammatory root resorption is not a rare finding in the pediatric community, with spread of infection....
Knowledge of infection prevention and control practices among health care workers caring for patients with suspected or confirmed COVID-19: a cross-sectional study
Eman H Elsebaie,Amany A Salem,Amal S Sedrak,Ahmed Ayad,Sahar A Ahmed,Bassante A El Razik,Noha M Abu bakr Elsaid
A pandemic of SARS-CoV2 was proclaimed on March 11, 2020.. Healthcare facilities associated infections is considered a serious public health problem.. According to the COVID-19 Situation Report by World Health Organization (WHO) 82, 52 countries had identified a total of 22,073 health care workers (HCWs) had caught COVID-19.. Ac....
Impact of ascorbic acid in reducing the incidence of vancomycin associated nephrotoxicity in critically ill patients: A preliminary randomized controlled trial
Nouran Hesham El-Sherazy,Naglaa Samir Bazan,Sara Mahmoud Shaheen,Nagwa A. Sabri
Vancomycin (a glycopeptide antibiotic) has been the first line of treatment for methicillin-resistant. Trough level between 15–20 mg/L was recommended in complicated infections caused by. The incidence of vancomycin associated nephrotoxicity (VAN) is high and may reach 10–20% upon administering the conventional dose of vancomyci....
Applying an ecological framework to examine the multiple levels of influence affecting the utilisation of private sector adult asthma services in Khartoum, Sudan: a mixed methods study
Rachael Thomson,Magde Noor,Asma Elsony
Asthma is the third most common cause of hospital visits in Sudan. Sudan has a pluralistic health care system, with a strong and varied private sector. While research examining public sector asthma services exists, very little is known about which asthma services are available in the private sector.. An explanatory sequential mi....
The impact of testing and treatment on the dynamics of Hepatitis B virus
Olajumoke Oludoun,Olukayode Adebimpe,James Ndako,Michael Adeniyi,Oluwakemi Abiodun,Babatunde Gbadamosi
Hepatitis is an inflammation/scarring of the liver that contributes to various health complications, including death. It occurs due to an immune system attack by the virus in the liver and damages this vital organ of the body in the process (. In highly endemic areas, the most common form of transmission of hepatitis B is from m....
Variations in sexual network connectivity may explain dramatic variations in sexually transmitted infection prevalence between populations and over time: a four-country analysis
Chris Kenyon
The reasons underpinning the dramatic variations in sexually transmitted infection (STI) incidence between different populations are incompletely understood. These insights provided the motivation for the current paper where we aimed to conduct a more systematic analysis of the association between network connectivity and STI pr....
Prevalence and factors associated with anemia among children under five years of age in Rombo district, Kilimanjaro region, Northern Tanzania
Innocent B. Mboya,Redempta Mamseri,Beatrice J. Leyaro,Johnston George,Sia E. Msuya,Melina Mgongo
Anemia in children under five years is a significant public health problem in low-, middle- and high-income countries. The world health organization (WHO) defines anemia as a low blood hemoglobin concentration of less than 11g/dl in children under five years of age. A variety of factors causes anemia, but the most common cause i....
Developing a Minimum Data Set for a congenital abnormalities surveillance programme in Rwanda – a modified e-Delphi consensus study
Annette Uwineza,Aline Muhorakeye,Janvier Hitayezu,Peter Thomas Cartledge
CARs, congenital abnormality registries; OMET, core outcome measures in effectiveness trials; COS, core outcome set; EUROCAT, European Surveillance of Congenital Anomalies; HRH, human resources for health; ICD, International Statistical Classification of Diseases and Related Health Problems; IRB, institutional review board; LMIC....
It’s the network, stupid: a population’s sexual network connectivity determines its STI prevalence
Chris R. Kenyon,Wim Delva
There is little consensus as to why the prevalence of bacterial vaginosis (BV), HIV and other sexually transmitted infections (STIs) varies so dramatically around the world. A range of explanations have been put forward, including variation in circumcision prevalencen