Case Report: Xanthogranulomatous prostatitis, a difficult differential diagnosis of prostate adenocarcinoma
Reda El Moussaoui,Ali El Moussaoui,Mohamed Dakir,Amal Benkirane
A variety of benign conditions of the prostate can clinically mimic prostatic adenocarcinoma, thus raising a diagnostic problem. Xanthogranulomatous prostatitis, a rare form of non-specific granulomatous prostatitis, is considered among those pathologies that can clinically, biochemically and even radiologically behave as a pros....
Risk assessment for the implementation of controlled human Schistosoma mansoni infection trials in Uganda
Jan Pieter Koopman,Moses Egesa,Anne Wajja,Moses Adriko,Jacent Nassuuna,Gyaviira Nkurunungi,Emmanuella Driciru,Gijsbert van Willigen,Stephen Cose,Maria Yazdanbakhsh,Pontiano Kaleebu,Narcis Kabatereine,Edridah Tukahebwa,Meta Roestenberg,Alison M. Elliott
Schistosomiasis is a parasitic infection affecting approximately 230 million people worldwide. Controlled human infection (CHI) studies are an important tool for vaccine development. They provide a platform to safely and swiftly test vaccine candidates for the pathogen in question. Furthermore, they can contribute to understandi....
Integrating environmental health and genomics research in Africa: challenges and opportunities identified during a Human Heredity and Health in Africa (H3Africa) Consortium workshop
Bonnie R. Joubert,Kiros Berhane,Jonathan Chevrier,Gwen Collman,Brenda Eskenazi,Julius Fobil,Cathrine Hoyo,Chandy C. John,Abera Kumie,Mark Nicol,Michèle Ramsay,Joshua Smith,Adrie Steyn,Desire Tshala-Katumbay,Kimberly McAllister
The Human Heredity and Health in Africa (H3Africa) initiative began as a joint effort of the National Institutes of Health (NIH) Common Fund Global Health Program and the Wellcome Trust, in partnership with the African Society of Human Genetics. H3Africa aims to support the establishment of a sustainable African research infrast....
Description and comparison of physical activity from self-reports and accelerometry among primary school children in Kilimanjaro, Tanzania: a pilot study
Mary Vincent Mosha,Elizabeth Kasagama,Philip Ayieko,Jim Todd,Sia E. Msuya,Heiner Grosskurth,Suzanne Filteau
Physical activity in children is the key to better health. Active children gain health benefits, including cardiorespiratory, muscular fitness and bone health. Physical activity plays a vital role in preventing non-communicable diseases (NCDs) and avoiding weight gain. Physical activity is a complex behaviour that includes day-t....
Impact of livestock interventions on maternal and child nutrition outcomes in Africa: A systematic review and meta-analysis protocol
Josphat Muema,Julius Oyugi,Zipporah Bukania,Mutono Nyamai,Christine Jost,Tewoldeberhan Daniel,Joseph Njuguna,Samuel Mwangi Thumbi
Undernutrition (stunting and wasting) remains a serious public health concern in Africa. Agriculture including livestock plays a key role as a source of food and nutrition security and livelihoods for a majority of rural households in sub-Saharan Africa. The impact pathways through which livestock interventions may influence hum....
High infectious disease burden as a basis for the observed high frequency of asymptomatic SARS-CoV-2 infections in sub-Saharan Africa
Kwadwo Asamoah Kusi,Augustina Frimpong,Frederica Dedo Partey,Helena Lamptey,Linda Eva Amoah,Michael Fokuo Ofori
The 2019 novel human coronavirus, named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is one of seven coronaviruses that cause respiratory and intestinal diseases in humans. COVID-19 has exposed weaknesses in health systems globally and pointed to the need to strengthen these health systems and also put a signifi....
Ethical challenges in community engagement practices in research during the COVID-19 pandemic in Africa
Paulina O. Tindana,Jantina De Vries,Dorcas Kamuya
When the World Health Organization declared coronavirus disease 2019 (COVID-19) a global health pandemic (. Following recommendations from WHO, many African countries including Ghana, Kenya and South Africa have responded to the pandemic by implementing strict measures to stop the importation of new cases and to curb community s....
Prices and sold amount dynamics, endogenous knowledge and distribution of Picralima nitida (Stapf) T. Durand and H. Durand across in the Dahomey Gap and Guinea-Congolese regions
Ghislain Comlan Akabassi,Elie Antoine Padonou,Achille Ephrem Assogbajo,Noël Zirihi Guede
is one of the most important medicinal plant species in the West and Central African folk medicine (. As a result of the above, the plant species are under threats at various levels management and based on data on the International Union Conservation for Nature (IUCN) Red List of Threatened plant species, there are no conservati....
COVID-19 and the HIV care continuum in Uganda: minimising collateral damage
Enock Kagimu,Emily M. Martyn,Jane Gakuru,John Kasibante,Morris K Rutakingirwa,Richard Kwizera,Kenneth Ssebambulidde,Darlisha Williams,Jayne Ellis,Fiona V Cresswell,David B. Meya
Coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first described in Wuhan, China in December 2019 and to date there have been more than 106,375,662 confirmed cases, with at least 2,321,294 deaths, globallyn
Case Report: Swallowed toothbrush in the stomach of a 56 year female at St Mary’s Hospital Lacor, Uganda
Derrick Amone,Christopher Okot,Patrick Mugabi,Tom Richard Okello,David Martin Ogwang
Toothbrush swallowing is a rare occurrencen
Effect of birth weight, exclusive breastfeeding and growth in infancy on fat mass and fat free mass indices in early adolescence: an analysis of the Entebbe Mother and Baby Study (EMaBs) cohort
Jonathan Nsamba,Swaib A. Lule,Benigna Namara,Christopher Zziwa,Hellen Akurut,Lawrence Lubyayi,Florence Akello,Josephine Tumusiime,Alison M. Elliott,Emily L. Webb
BMI - Body mass index. CI - Confidence interval. EMaBS- Entebbe Mother and Baby Study. FM - Fat mass. FMI - Fat mass index. FFM - Fat free mass. FFMI - Fat free mass index. NCDs - Non-communicable diseases. SD - Standard deviation
Organizing and running bioinformatics hackathons within Africa: The H3ABioNet cloud computing experience
Azza E. Ahmed,Phelelani T. Mpangase,Sumir Panji,Shakuntala Baichoo,Yassine Souilmi,Faisal M. Fadlelmola,Mustafa Alghali,Shaun Aron,Hocine Bendou,Eugene De Beste,Mamana Mbiyavanga,Oussema Souiai,Long Yi,Jennie Zermeno,Don Armstrong,Brian D. O'Connor,Liudmi
As an inherently interdisciplinary science, bioinformatics depends upon complementary expertise from biomedical scientists, statisticians and computer scientists. On the African continent, there is generally limited access to such events. However, with the growing capacity for Africans to generate genomic data, the need to analy....
A hundred years of rabies in Kenya and the strategy for eliminating dog-mediated rabies by 2030
Austine O Bitek,Eric Osoro,Peninah M Munyua,Mark Nanyingi,Yvonne Muthiani,Stella Kiambi,Mathew Muturi,Athman Mwatondo,Rees Muriithi,Sarah Cleaveland,Katie Hampson,M. Kariuki Njenga,PM Kitala,Samuel Mwangi Thumbi
Every year rabies is estimated to kill around 59,000 (95% CI: 25-159,000) people globally, with the vast majority of rabies deaths occurring in rural Africa and Asia. In Kenya, rabies has been a public health problem since the first case was reported in a dog in the outskirts of Nairobi in 1912, and in a woman from the Lake Vict....
Screening tools for HIV-associated neurocognitive disorders among adults living with HIV in sub-Saharan Africa: A scoping review
Patrick N. Mwangala,Charles R. Newton,Melanie Abas,Amina Abubakar
With the advent of highly active antiretroviral therapy (HAART), the 25 million people living with HIV-1/AIDS in sub-Saharan Africa (SSA) now have the potential for a near-normal life expectancy. The prevalence of HAND is estimated to be high across regions, occurring in as many as 50% of all adults living with HIV, including th....
Environmental and biological monitoring in the workplace: A 10-year South African retrospective analysis
Puleng Matatiele,Lerato Mochaki,Bianca Southon,Boitumelo Dabula,Poobalan Poongavanum,Boitumelo Kgarebe
Humans are exposed to hazardous chemicals in a variety of ways; mainly through diet and through the air that we breathe (indoor, outdoor and occupational). Occupational exposure can occur through inhalation, absorption through the skin or ingestion, with the inhalation of vapours, dusts, fumes or gases being the route of highest....
Case Report: Biloma gastrostomy after failed sonogram-guided percutaneous aspiration, pigtail catheter insertion and surgical drainage
Tom R. Okello,Davidson Ocen,Jimmy Okello,Irene Pecorella,Derrick Amone
Biloma is a rare but challenging condition in Uganda and Sub-Saharan Africa. The term biloma was introduced in 1979 by Gould and Pater to describe a loculated bile collection located outside the biliary treen
Institutionalizing research capacity strengthening in LMICs: A systematic review and meta-synthesis
Marta Vicente-Crespo,Ojo Agunbiade,John Eyers,Margaret Thorogood,Sharon Fonn
There has been a growth in investment for research capacity development in institutions in low- and middle-income countries (LMICs). However, the long-term success and sustainability of increased research capacity depend on the degree to which successful interventions are mainstreamed within the routine functioning of institutio....
Global CO 2 emission reduction policies and West African electricity system: Case for transformational access
Abiodun Suleiman Momodu,Ahmad Addo
Across West Africa, more than 230 million people are without electricity access, translating to about 66% of the entire population. This means that making access available represents a life-or-death issue for the sub-region; it is estimated on a yearly basis that 3.5 million people die from indoor air pollution caused by the use....
Using the Drama of DNA approach to community engagement in genomic research in South Africa: experiences and lessons learnt
Marlyn C. Faure,Ambroise Wonkam,Jantina De Vries
Genomic research and rapidly evolving related technologies, such as next-generation sequencing and genome editing, raise important questions relating to their ethical, legal and social dimensions. One method that uses drama to engage people around ethical challenges of genomics research is the Drama of DNA approach which was dev....
Typology, technical efficiency and scale economy of dibiteries in Dakar, Senegal
Malik Orou Seko,Walter Ossebi,Gnamien Sylvain Traoré,Andrée Prisca Ndjoug Ndour,Jasmina Saric,Gilbert Fokou,Daouda Dao,Bassirou Bonfoh
In Senegal, livestock management occupies nearly two-thirds of the country's agricultural households and constitutes, together with agriculture, the main activity of the rural populations and the main supplier of food and income. The livestock subsector has experienced a real dynamism in recent years, with sustained performances....
The quality of public sources of drinking water in oil-bearing communities in the Niger Delta region of Nigeria
Omosivie Maduka,Benson Ephraim-Emmanuel
Nigeria is Africa’s largest producer of crude oil and the sixth largest producer in the world, (. A large proportion (97%) of the revenue from foreign trade that comes to Nigeria is from export of crude oil. As much as 20% of the country’s GDP and 65% of the revenue budget is sourced from crude oil. Alongside the vast deposit of....
Heart Failure in End of Life Care
Amy Gadoud, Karen Hogg, Shona Jenkins and Yvonne Millerick
This session has been written by a multidisciplinary group of cardiology and palliative care specialists to help palliative care clinicians become more confident with managing patients with heart failure and knowing when to liaise with heart failure services.
Factors associated with research productivity in higher education institutions in Africa: a systematic review
Dieudonne Uwizeye,Florah Karimi,Caroline Thiong'o,Jackline Syonguvi,Vollan Ochieng,Francis Kiroro,Alex Gateri,Anne M. Khisa,Hesborn Wao
There is a close association between research and development, both of which play a crucial role in economic growth (. Similarly, funding for research has remained low in most of the countries in Africa (. The situation described above suggests that African countries need to re-consider their research agenda taking cognizance of....
Five ways to wellbeing
Gregor Henderson
This session enables you to be confident in talking with clients and patients about the things they can do to help improve and maintain their wellbeing. This will help in giving your patients the confidence they need about staying physically and mentally well. The session will also help provide a good understanding for how yo....
Outbreak of a New COVID 19: What Anaesthetists Should Know
Philip W. H. Peng, Pak-Leung Ho and Susy S. Hota
This course depicts what anaesthetists need to know in response to this outbreak of Covid-19.