Novel multiplex assay for profiling influenza antibodies in breast milk and serum of mother-infant pairs
Kirsi M. Järvinen,Jiong Wang,Antti E. Seppo,Martin Zand
The immune system in neonates and young infants is initially immature, without adequate protection against infections. The dogma is that during infancy, systemic protection is passively provided by transplacental transfer of IgG antibodies and oral and gastrointestinal mucosal protection via breast milk (BM) containing predomina....
Blood Interferon Signatures Putatively Link Lack of Protection Conferred by the RTS,S Recombinant Malaria Vaccine to an Antigen-specific IgE Response
Darawan Rinchai,Scott Presnell,Marta Vidal,Sheetij Dutta,Virander Chauhan,David Cavanagh,Gemma Moncunill,Carlota Dobaño,Damien Chaussabel
About 3.4 billion people, nearly half of the world’s population, live in areas at risk of n
Prevalence of antibiotic-resistant E. coli in retail chicken: comparing conventional, organic, kosher, and raised without antibiotics
Jack M Millman,Kara Waits,Heidi Grande,Ann R Marks,Jane C Marks,Lance B Price,Bruce A Hungate
The use of antibiotics in livestock production may pose health risks to humans, as such usage has been correlated with the occurrence of antibiotic-resistant bacteria isolated from human infections. The organic and RWA labels require specific production methods as stipulated in US federal regulations, whereas the kosher label ad....
Fluoxetine pharmacokinetics and tissue distribution suggest a possible role in reducing SARS-CoV-2 titers
Andy R. Eugene
The selective serotonin reuptake inhibitor (SSRI) fluoxetine is a racemic mixture of two stereoisomers,. Considering the COVID-19 clinical symptoms affecting the lungs, fluoxetine lung concentrations would be an important factor to consider when interpreting any study results. Johnson n
In vitro evaluation of the anti-diabetic potential of Helichrysum petiolare Hilliard & B.L. Burtt using HepG2 (C3A) and L6 cell lines
Adebowale Emmanuel Aladejana,Graeme Bradley,Anthony Jide Afolayan
Diabetes mellitus (DM) is a complex multi-factorial metabolic anomaly characterized by glucose intolerance and hyperglycaemia, either due to relatively impaired insulin secretion or reduced effectiveness of insulin in facilitating glucose uptake. The worldwide prevalence of diabetes has increased drastically in the last 30 years....
In silico screening of known small molecules to bind ACE2 specific RBD on Spike glycoprotein of SARS-CoV-2 for repurposing against COVID-19
Bharath BR,Hrishikesh Damle,Shiban Ganju,Latha Damle
The complete genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is 82% identical to SARS-CoV, both viruses share a common clade encompassing the genus. Drug repurposing is a commercially viable strategy, as it exploits existing drugs, thus significantly reducing the cost and time involved in developing effect....
Does the mouse tail vein injection method provide a good model of lung cancer?
Nensi Shrestha,Zabeen Lateef,Orleans Martey,Abigail R. Bland,Mhairi Nimick,Rhonda Rosengren,John C. Ashton
Lung cancer causes more deaths worldwide than any other cancer in both males and females. Mouse models of lung cancer fall into several categories. The first division that can be made is whether the cancer cells are of mouse or human origin. Cancer cells of mouse origin may be grafted onto a host mouse, or induced in tissues by....
Cardiovascular Physiology Relevant to Conscious Sedation
John Lyne
This session covers cardiovascular physiology relevant to conscious sedation.
Central Mediators of Pain
Ian Fletcher
This session is designed to give the learner a basic understanding of how pain is experienced and analysed within the central nervous system (CNS), and of the factors which may alter this experience. This session is designed to give the learner a basic understanding of how pain is experienced and analysed within the central nerv....
Dental Local Anaesthetic Agents
Hannah Desai and Kathy Wilson
This session describes the common structure of injectable local anaesthetics (LAs) along with their action on neurotransmission. It also discusses the effect the body has on LAs, from administration to excretion. The use of vasoconstrictors in dental LAs will be considered.
Alcohol Impairment: Basic Medicolegal Issues for the Toxicology and Addiction Specialist
Gloria J. Baciewic and Timothy J. Wiegand
1.25 Hours
A Deep Dive into Complex Addiction Cases with Leading Experts! The ACMT Addiction Toxicology Case Conference webinar series discusses Addiction/Toxicology cases in an interactive fashion featuring experts from Addiction Medicine, Addiction Psychiatry, and Medical Toxicology. Case 1: Intoxication and safe clearance from the....
Motivating Patients
Grant Simic, BMedSci
1.00 Hours
Overcome patient ambivalence, discuss the issue of change with patients, and improve patient experience. This interactive online course shows how to identify when a patient is ready for change, uncover personal drivers for lifestyle changes, gain patient commitment, and improve treatment adherence.
Orthopaedic Clinical Examination
Abdullah Hanoun, Sriram Srinivasan
2.00 Hours
Deepen your knowledge of orthopaedic physical exam techniques. Gain practical insights for confident clinical assessment and decision making.
Principles of Orthopaedic Imaging and Case Spottors
David Hughes, Piyush V. Gavai, Justin Mooteeram, Dr. Nicola Evans
4.50 Hours
Deepen your knowledge of orthopaedic imaging modalities. Sharpen your diagnostic abilities through interactive case studies.
Orthopaedics Pathologies & Oncology
S. Kamat, Mr. Akhil Kapoor, Mr. Vilas Sadekar
2.50 Hours
Deep dive into orthopaedic disorders & injuries. Explore the role of oncology in bone & soft tissue tumors.
The Theory of Implicit Bias and Strategies to Remedy Implicit Bias
Broc Pollinger
0.75 Hours
This CE activity will define implicit bias and provide the learner with an understanding of how implicit bias negatively impacts access to care, treatment, and patient outcomes. In addition, strategies to remedy the negative impact of implicit bias and reduce disparities in healthcare access and delivery also will be discussed.....
Fellows' Experience with Micro and Macro Initiation
Gloria J. Baciewic and Timothy J. Wiegand
1.25 Hours
A Deep Dive into Complex Addiction Cases with Leading Experts! The ACMT Addiction Toxicology Case Conference webinar series discusses Addiction/Toxicology cases in an interactive fashion featuring experts from Addiction Medicine, Addiction Psychiatry, and Medical Toxicology. Case 1: Low Dose Initiation Case 2: 'Macro Indu....
Contraception and Family Planning: How Does Each Method Work to Prevent Pregnancy?
Mark Hathaway, Erica Chin, Jacqueline Willie, Alice Muraguri
This course contains information on female anatomy, menstruation, ovulation, and fertilization. As a provider of family planning and contraception counselling and services, this course will equip you to guide postpartum women’s choices in sexual and reproductive health and rights (SRHR), reproductive empowerment, and bodily auto....
Managing Type 2 Diabetes in General Practice eLearning
Jeshni Amblum-Almer and Gill Dunn
3.00 Hours
The course provides essential knowledge and skills for all healthcare professionals in primary care, enabling effective management of diabetic patients using an evidence-informed and patient-centered approach. The course aims to equip healthcare professionals with the necessary knowledge and skills to manage diabetic patients....
Module 1: Overview and Introduction
Tania Farha and Riet Groenen, Upala Devi and Luis Mora, Claudia Garcia Moreno and Avni Amin, Suki Beavers, Niki Palmer and Charles Chauvel, Claudia Baroni and Sven Pfeiffer
Module 1 offers an introduction to the Package, as well as foundational elements and information on how to use this tool.
Handling Large Molecular Waste Containing Guanidine Thiocyanate: Pilot in Uganda & Nigeria
Mr Joel Peter Opio and Dr Ughweroghene Kingston Omo-Emmanuel
LabCoP’s Waste Management Sub CoP ECHO session, held on 18 July 2024, focused on Handling Large Volume Molecular Liquid Waste Containing Guanidine Thiocyanate and pilot studies from Nigeria and Uganda. Given the scale up of viral load (VL) testing and early infant diagnosis (EID) of HIV globally over the last decade, there has b....
GIS Platforms for AMR, One Health, and Pandemic Preparedness
Stephen Obol Opiyo
In this Antimicrobial Resistance Community of Practice (AMR CoP) webinar, we review the highlights of a groundbreaking study aimed at enhancing global antimicrobial resistance research capabilities, using interactive geographic information system (GIS) dashboards developed to enable comprehensive data analysis of AMR across mult....
Early Adoption of WHO Standard for Universal Rapid TB Diagnostics
Mr David Asiimwe and Dr Omoniyi Amos
On 9 May 2024, ASLM’s LabCoP convened an Extended ECHO session on implementation experiences from early adopters of the World Health Organization Standard on Universal Access to Rapid Tuberculosis Diagnostics, released by WHO in 2023. The standard comprises 12 benchmarks in four steps of the diagnostic cascade, including: identi....
Cartridge Waste Management in VL Testing: The Mouse in the Room
Edward Krisiunas and Rumbidzai Ndungwani
ASLM’s LabCoP, in conjunction with Cepheid, convened a Waste Management Sub-CoP ECHO session focusing on GeneXpert cartridge waste management at viral load (VL) testing laboratories. GeneXpert is one of the test devices widely used in multi-disease testing, with substantial placement in most laboratory networks in Africa. The su....
Lab Mapping journey and final data use: Experience from Malawi and Zimbabwe
Thresa Sumani, and Vincent Kampira
On 13 June, ASLM’s LabCoP hosted an Extended ECHO session about Malawi and Zimbabwe experiences with lab mapping and final data use. ASLM, Africa CDC and partners have been supporting countries in a phased manner to map existing laboratory capacity on the continent. This initiative aims at collecting laboratory data linked to ge....